Sickle cell disease and selection

Sickle cell disease and selection
Type of Resource: Practical activity/investigation

This web page gives details of an activity where students simulate the natural selection of the sickle cell alleles, using beans and a flipped coin. They should find that the sickle cell allele rapidly becomes more common where there is a high incidence of malarial infection, an example of natural selection in practice.

Additional Information

This activity has been produced by the Nuffield foundation in partnership with the Society of Biology (UK) and is found on the Nuffield foundation website.

Related resources

The making of the fittest: Natural selection in humans: http://www.hhmi.org/biointeractive/making-fittest-natural-selection-humans (last accessed 24 February 2016).

Australian Curriculum:
  • Year 10 > Science Inquiry Skills > Evaluating > Evaluate conclusions, including identifying sources of uncertainty and possible... > ACSIS205
  • Year 10 > Science Inquiry Skills > Processing and analysing data and information > Analyse patterns and trends in data, including describing relationships between... > ACSIS203
  • Year 10 > Science Inquiry Skills > Processing and analysing data and information > Use knowledge of scientific concepts to draw conclusions that are consistent... > ACSIS204
  • Year 10 > Science Inquiry Skills > Questioning and Predicting > Formulate questions or hypotheses that can be investigated scientifically > ACSIS198
  • Year 10 > Science Understanding > Biological Sciences > The theory of evolution by natural selection explains the diversity of living... > ACSSU185
  • Year Senior Secondary > Science Inquiry Skills > Evaluating
  • Year Senior Secondary > Science Inquiry Skills > Processing and analysing data and information
  • Year Senior Secondary > Science Inquiry Skills > Questioning and Predicting
  • Year Senior Secondary > Science Understanding > Biological Sciences